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Our projection model predicts the Arizona Cardinals will take down the Green Bay Packers on Sunday, Oct. 19 at 4:25 p.m. ET. For a complete projection on the matchup at State Farm Stadium, which includes our prediction on the spread, over/under, and final score, keep reading.
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Packers vs. Cardinals Game Info and TV Channel
- When: Sunday, October 19, 2025 at 4:25 p.m. ET
- Where: State Farm Stadium in Glendale, Arizona
- TV: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Listen to the game on 97.3 The Game
Packers vs. Cardinals Odds and Betting Info
- Spread favorite: Packers (-7)
- Moneyline: Packers (-377), Cardinals (+296)
- Total: 44.5 points
Packers vs. Cardinals Prediction
- Pick ATS: Cardinals (+7)
- Pick OU: Over (44.5)
Prediction:
Cardinals 23 - Packers 22
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Packers vs. Cardinals Betting Insights
- The Packers have covered twice in five chances against the spread this season.
- The Cardinals are 3-3-0 ATS this year.
- Green Bay has been favored by 7 points or more this season twice, and failed to cover both times.
- Arizona has covered the spread when playing as at least 7-point underdogs in its only opportunity this season.
- So far this season, two Packers games have hit the over.
- In 2025, three Cardinals games have hit the over.
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