When the Green Bay Packers square off against the Cleveland Browns at 1 p.m. ET on Sunday, Sept. 21, our projection system predicts the Packers will take home the win. Our model also projects the spead, point total, and final score, which you can see below.
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Packers vs. Browns Game Info and TV Channel
- When: Sunday, September 21, 2025 at 1 p.m. ET
- Where: Huntington Bank Field in Cleveland, Ohio
- TV: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Listen to the game on 97.3 The Game
Packers vs. Browns Odds and Betting Info
- Spread favorite: Packers (-7.5)
- Moneyline: Packers (-452), Browns (+348)
- Total: 41.5 points
Packers vs. Browns Prediction
- Pick ATS: Packers (-7.5)
- Pick OU: Over (41.5)
Prediction:
Packers 30 - Browns 13
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Packers vs. Browns Betting Insights
- The Packers have a record of 2-0-0 against the spread this season.
- The Browns have covered once in two games against the spread this year.
- Cleveland has not covered the spread when an underdog by 7.5 points or more this year (in one opportunity).
- So far this season, none of the Packers' games have hit the over.
- Browns games have gone over the point total once this season.
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